Research progress of cancer stem cells in triple-negative breast cancer
10.3760/cma.j.issn.1673-422X.2019.06.010
- VernacularTitle:三阴性乳腺癌干细胞研究进展
- Author:
Ye KANG
1
;
Jianyi LI
;
Xianghong YANG
Author Information
1. 中国医科大学附属盛京医院病理科
- Keywords:
Breast neoplasms;
Neoplastic stem cells;
Therapy;
Drug resistance;
Triple negative breast neoplasms
- From:
Journal of International Oncology
2019;46(6):362-365
- CountryChina
- Language:Chinese
-
Abstract:
There are abundant cancer stem cells (CSCs) in triple-negative breast cancer TNBC).CSCs can maintain their phenotype by unique molecular mechanism and tumor microenvironment,and can promote the chemotherapy resistance and recurrence of TNBC.Blocking these key molecules or altering tumor microenvironment can reduce CSCs,and then inhibited cancer growth and reverse chemotherapy resistance of TNBC.
