M2 macrophage marker CD206 and tumor
10.3760/cma.j.issn.1673-422X.2019.03.009
- VernacularTitle:M2型巨噬细胞标志物CD206与肿瘤
- Author:
Yue LI
1
;
Lei GAO
;
Hongchang LI
;
Hongjie YU
;
Yong ZHANG
Author Information
1. 上海中医药大学附属普陀医院中心实验室 200333
- Keywords:
Neoplasms;
M2 macrophage;
CD206
- From:
Journal of International Oncology
2019;46(3):174-177
- CountryChina
- Language:Chinese
-
Abstract:
Tumor-associated macrophages exist in all stages of tumor progression,and stimulate angiogenesis and invasion of tissues.M2 macrophages are predominant.CD206 is a M2 macrophage marker with high specificity and plays an important role in tumor cell proliferation and metastasis.Studies have shown that CD206 is closely related to malignant tumors such as breast cancer,ovarian cancer,pancreatic cancer and prostate cancer.Deepening the research on CD206 has certain clinical guiding significance for expounding the formation mechanism of tumor immune microenvironment and finding more targeted drugs.
