Research progress in the role of gut microbiota in human diseases
10.3760/cma.j.issn.1673-4181.2019.03.013
- VernacularTitle:肠道微生物与人类疾病的研究进展
- Author:
Hua LIN
1
;
Minglin OU
;
Jiejing CHEN
;
Weiguo SUI
Author Information
1. 中国人民解放军联勤保障部队第九二四医院肾脏科
- Keywords:
Immunity;
Gut microbiota;
Intestinal diseases
- From:
International Journal of Biomedical Engineering
2019;42(3):258-262
- CountryChina
- Language:Chinese
-
Abstract:
Gut Microbial species have different physiologic functions, such as digestion, nutrition, immunity, etc. Studies have shown that gut microbiota plays an important role in intestinal function. Gut microbiota is a complex ecosystem that participates in the physiological and pathological processes of the human body and forms a dynamic equilibrium with the human body. If this balance is broken, it may lead to or aggravate the occurrence and development of diseases. In recent years, researches have confirmed that the biological composition of gut microbiota in patients with diseases is significantly different from that of healthy people. The detection and transformation of gut microbiota has certain value and therapeutic effect on the diagnosis of diseases. Systematic biological methods can be used to study the relationship between gut microbiota and immunity and metabolism. In this paper, the related researches on the interactions between gut microbiota and human diseases were reviewed, including immunodeficiency-related diseases, autoimmune diseases, celiac diseases, intestinal microbial-related metabolic diseases and neurological diseases, and the related pathogenesis was summarized as well.
