piRNA and cerebral ischemia
10.3760/cma.j.issn.1673-4165.2019.07.013
- VernacularTitle:piRNA与脑缺血
- Author:
Taoyan PANG
1
;
Meiyan CHEN
;
Haixia WEN
;
En XU
Author Information
1. 广州医科大学神经科学研究所
- Keywords:
Brain ischemia;
RNA,small interfering;
Epigenomics
- From:
International Journal of Cerebrovascular Diseases
2019;27(7):549-555
- CountryChina
- Language:Chinese
-
Abstract:
Piwi-interacting RNA (piRNA) is a new class of small non-coding RNAs that function by specifically binding to the Piwi subfamily members of the Argonaute protein family. piRNA regulates the expression of target genes at epigenetic and post-transcriptional levels, and participates in the development and progression of cerebral ischemia by mediating pathophysiological processes such as inflammation, angiogenesis, and neuronal synaptic plasticity.
