Treatment of ischemic stroke with bone marrow mesenchymal stem cells:directional differentiation of neural lineage
10.3760/cma.j.issn.1673-4165.2019.07.012
- VernacularTitle:骨髓间充质干细胞治疗缺血性卒中:神经谱系定向分化
- Author:
Zhigang LUN
1
;
Jiajia TANG
;
Changsheng ZOU
;
Jing HUANG
;
Aimin LI
Author Information
1. 徐州医科大学附属连云港医院神经外科
- Keywords:
Stroke;
Brain ischemia;
Bone marrow cells;
Mesenchymal stem cells;
Neurons;
Cell differentiation
- From:
International Journal of Cerebrovascular Diseases
2019;27(7):543-548
- CountryChina
- Language:Chinese
-
Abstract:
Studies have shown that bone marrow mesenchymal stem cells (BMSCs) transplantation can restore the sensory and motor function of patients with ischemic stroke. BMSCs transplantation is a promising therapeutic strategy because of its ability to differentiate into neuron-like cells. This article reviews the inducers that promote BMSCs to differentiate into neuron-like cells in vitro.