Advance in MRI assessment of white matter injury and brain development in premature infants
10.3760/cma.j.issn.1673-4408.2019.05.005
- VernacularTitle:早产儿脑白质损伤及损伤后脑发育MRI评价研究进展
- Author:
Zijian QIN
1
Author Information
1. 南方医科大学附属珠江医院儿科中心
- Keywords:
White matter injury;
Brain development;
Premature infant
- From:
International Journal of Pediatrics
2019;46(5):327-330
- CountryChina
- Language:Chinese
-
Abstract:
Premature white matter injury (WMI) is the immature white matter injury caused by ischemia,hypoxia and inflammation,which will affect normal neurodevelopment process and cause poor neurological outcomes.MRI has been widely used in early diagnosis of WMI because it can reflect the anatomical and pathological changes of WMI in premature infants.Functional MRI,such as diffusion-tensor imaging and magnetic resonance spectroscopy,can help quantitative assessment of the severity of WMI and neurodevelopment process so as to predict its neurodevelopment prognosis.This review summarizes the progresses in the application of MRI in the quantitative assessment of WMI and brain development in preture infants and its neurological outcomes.
