Estimation of spectral oscillatory power of resting-state EEG in subjective tinnitus

Yuexin Cai; Jiahong LI; Haidi Yang; Ling Chen; Yingfeng Sun; Xiayin Huang; Hao Xiong; Suijun Chen; Xiaoting Chen; Guisheng Chen; Yanhong Chen; Yiqing Zheng

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Estimation of spectral oscillatory power of resting-state EEG in subjective tinnitus

VernacularTitle:主观性耳鸣患者静息态脑电地形图功率频谱研究
Author: Yuexin CAI ¹ ; Jiahong LI ; Haidi YANG ; Ling CHEN ; Yingfeng SUN ; Xiayin HUANG ; Hao XIONG ; Suijun CHEN ; Xiaoting CHEN ; Guisheng CHEN ; Yanhong CHEN ; Yiqing ZHENG
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1. 中山大学孙逸仙纪念医院耳鼻咽喉头颈外科
Keywords: Tinnitus; Electroencephalography; Loudness Perception; resting state; spectral oscillatory power
From: Chinese Archives of Otolaryngology-Head and Neck Surgery 2018;25(7):358-362
CountryChina
Language:Chinese
Abstract: OBJECTIVE To explor e the characteristics of spectral oscillatory power of resting-state electroencephalography(EEG) in subjective tinnitus patients and to lay the foundation for study of central mechanism of tinnitus.METHODS 31 subjects(15 subjects with subjective tinnitus and 16 age matching healthy subjects) underwent a 128-channel resting-state EEG analyses. After a series of preprocessing, data were segmented into 8 frequency bands, including δ(0.5～3.5 Hz), θ(4～7.5 Hz), α1(8～10 Hz), α2(10～12 Hz), β1(13～18 Hz), β2(18.5～21 Hz), β3(21.5～30 Hz) and γ(30.5～44 Hz). The group differences of spectral power were analyzed by independent t test. Correlation between spectral power of each frequency band and tinnitus subjective symptoms were also analyzed. RESULTS Significant higher spectral power of the α1, β and γ bandwere found in the left and right temporal areas of tinnitus group compared with that of normal group.Tinnitus subjects also had higher spectral powerof the δ and θ band in temporo-parietal areas than that of the normal group. There was no significant difference of spectral power in other frequency bands. Moreover, signif icant positive cor relation were found between tinnitus loudness and spectralpower of right anterior lateral(R=0.66, P =0.007) and right anterior medial(R=0.58, P =0.031) areas. CONCLUSION Tinnitus subjects have higher spectral oscillatory power on right and left temporal lobe and temporo-parietal area. A positive correlation exsit between tinnitus loudness andspectral power of right anterior lateral and medial areas in tinnitus subjects, whichindicate that central reorganizationexsit in tinnitus reorganization andγ band maybe considered as a possible biomarkerforthe tinnitus subjective symptom.