Progress of CD5-positive diffuse large B-cell lymphoma

VernacularTitle:CD5阳性弥漫大B细胞淋巴瘤研究进展
Author: Yu TIAN ¹ ; Wei SANG ; Kailin XU
Author Information

1. 徐州医科大学附属医院血液科徐州医科大学血液病研究所 221000
Keywords: Lymphoma,large B-cell,diffuse; CD5; Antineoplastic combined chemotherapy protocols; Prognosis
From: Journal of Leukemia & Lymphoma 2019;28(6):378-381
CountryChina
Language:Chinese
Abstract: CD5-positive diffuse large B-cell lymphoma (CD5+DLBCL) is a special type of DLBCL, which is characterized with later clinical staging, high-risk of relapse in extranodular tissues like bone marrow and central nervous system (CNS).Combined chemotherapy including rituximab and salvage autotransplantation/ allotransplantation can not significantly improve the prognosis. This article reviews the clinicopathological features, the possible pathogenesis, treatment status and dilemma in order to get the better understanding of CD5+DLBCL and avail the early diagnosis and individualized treatment.