Progress of the correlation between apoptosisˉrelated genes and diffuse large Bˉcell lymphoma

VernacularTitle:凋亡相关基因与弥漫大B细胞淋巴瘤相关性的研究进展
Author: Wei WEI ¹ ; Xinjiang ZHU ; Shuchen CHEN ; Yuzhu DIAO ; Zhiying HU ; Xiaoling LI
Author Information

1. 大连医科大学临床肿瘤学院辽宁省肿瘤医院胸内一科
Keywords: Lymphoma,large Bˉcell,diffuse; Apoptosisˉrelated genes; Prognosis
From: Journal of Leukemia & Lymphoma 2019;28(5):314-318
CountryChina
Language:Chinese
Abstract: The apoptosisˉrelated gene is an important gene in the human body, and maintains the apoptosis process through the synergistic action of antiˉapoptosis and proˉapoptosis. Abnormal expressions of apoptosisˉrelated genes and their proteins play important roles in the development of diffuse large Bˉcell lymphoma (DLBCL). Recent studies have shown that targeting apoptosisˉrelated genes have potentials in the treatment of lymphoma, and the treatment of Bclˉ2 inhibitors and Bax activators combined with chemotherapy has attracted much attention. This article reviews the progress of apoptosisˉrelated genes and DLBCL.