Surgical treatment and prognostic analysis of thymic carcinoma: a report of 38 cases
- VernacularTitle:38 例胸腺癌的外科治疗及预后分析
- Author:
ZHU Chengxiang
1
,
2
;
WANG Wei
3
;
HUANG Chenjun
3
;
LI Qifan
3
;
ZHUANG Yu
3
;
YU Yue
3
Author Information
1. 1. Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, P.R. China
2. 2. Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital of Traditional Chinese Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing, 210001, P.R. China
3. Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, P.R. China
- Publication Type:Journal Article
- Keywords:
Thymic carcinoma;
prognosis;
surgery;
radical resection
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2019;26(11):1092-1097
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the influence of clinical, pathological and treatment factors on the prognosis of thymic carcinoma patient accepted surgical treatment. Methods Retrospective analysis was performed on 38 patients with thymic carcinoma undergoing surgical treatment between January 2008 and December 2017. The association between the prognostic factors including age, sex, thymectomy, radical resection, pathological type, TNM stage, Masaoka-Koga stage, tumor size, and survival was assessed using the Kaplan-Meier method. Results The 5-year overall survival rate of our cohort was 51.9%. Kaplan-Meier univariate survival analysis showed that radical resection (P=0.003), TNM stage (P=0.038), Masaoka-Koga stage (P=0.033), and tumor size (P=0.030) were related to the prognosis of patients with thymic carcinoma. Radical resection was also validated as an independent prognostic factor in multivariate Cox analysis (P=0.009, hazard ratio 2.31, 95%CI 1.23-4.33). Conclusion Radical surgical treatment could improve the prognosis of patients with resectable thymic carcinoma.
