Single-center retrospective analysis of 125 donor hearts from brain death donation and to explore the use of marginal donor hearts
- VernacularTitle:125 例脑死亡捐献心脏供体的单中心回顾性分析及边缘供心使用探讨
- Author:
WU Min
1
,
2
;
WU Yijing
1
,
2
;
WU Meifen
1
,
2
;
MAI Mingjie
1
,
2
;
HUANG Jingsong
1
,
2
;
CHEN Oudi
1
,
2
Author Information
1. Department of Cardiac Surgery, Guangdong Academy of Medical Sciences, Guangdong Provincial People&rsquo
2. s Hospital, Guangdong Cardiovascular Institute, Guangzhou, 510080, P. R. China
- Publication Type:Journal Article
- Keywords:
Heart transplantation;
marginal donor heart;
mitral regurgitation;
tricuspid regurgitation;
coronary calcification
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2019;26(11):1069-1073
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the assessment and maintenance of 125 donor hearts from brain death donation and explore the use of marginal donor hearts. Methods A retrospective analysis was conducted on the evaluation, maintenance, operation and follow-up results of 125 donor hearts from April 2016 to August 2019. There were 98 males and 27 females at age of 6-50 (36.0±2.4) years. Results Twelve donor hearts were discarded due to unqualified evaluation after heart harvest. 113 patients of heart transplantation were performed with a double lumen venous anastomosis manner. The mean time of cold ischemia was 220.1±6.7 min. Four patients died within 30 days after operation. Postoperative right ventricular assist circulation was performed in 4 patients, intra-aortic balloon counterattack (IABP) in 12 patients and extracorporeal membrane oxygenation (ECMO) in 12 patients. Marginal donors included 15 hepatitis B antigen positive donor hearts, 2 tricuspid regurgitation, 1 mitral regurgitation, 5 coronary calcification, 4 myocardial stunning and 2 severe weight mismatch. The results of follow-up (2 years) after marginal donor heart transplantation were satisfactory. Conclusion Improving the assessment and maintenance of donor hearts can improve the utilization rate of the heart, and the marginal donor heart transplantation needs long-term follow-up.
