Clinical and Laboratory Finding of the 2009 Pandemic influenza A (H1N1) in Children.
- Author:
Yu Rak SOHN
1
;
Su Hyun PARK
;
Won Duck KIM
Author Information
1. Department of Pediatrics, Fatima Hospital, Daegu, Korea. neogubugi@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
H1N1;
Pneumonia;
Asthma;
Oseltamivir
- MeSH:
Asthma;
Bronchopneumonia;
Child;
Disease Outbreaks;
Humans;
Immunoglobulins;
Infant;
Influenza A Virus, H1N1 Subtype;
Influenza, Human;
Inpatients;
Critical Care;
Lung;
Oseltamivir;
Outpatients;
Oxygen;
Pandemics;
Pneumonia;
Respiration;
Retrospective Studies;
Reverse Transcriptase Polymerase Chain Reaction;
Ventilators, Mechanical;
Viruses
- From:Korean Journal of Pediatric Infectious Diseases
2011;18(2):173-181
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: 2009 Pandemic influenza A (H1N1) virus was identified in March 2009 and subsequently caused worldwide outbreaks. We described the clinical and epidemiological characteristics of H1N1 influenza infection. METHODS: We used retrospective medical chart reviews to collect data on the visiting patients from a single institute. H1N1 infection was confirmed in specimens with the use of a RT-PCR (real time reverse transcriptase polymerase chain reaction assay). RESULTS: 6,836 patients had H1N1 RT-PCR test, and 2,781 were confirmed with H1N1 virus infection. 158 patients (5.7%) had hospital treatment and inpatients were significantly younger (5.4+/-3.3 years) than outpatients (7.5+/-3.9 years) among H1N1 virus confirmed patients. Oxygen, steroid, immunoglobulin, ventilator treatment was provided in a substantial proportion among pneumonia patients accompanying wheezy respiration. In addition more intensive care was needed in patients accompanying segmental, lobar, interstitial, mixed pneumonia and lung effusion (27.2%) than patients with bronchopneumonia (7.3%) among H1N1 virus infection confirmed patients. Seventy-one infants had oseltamivir treatment out of 83 infants under 1 year, and no significant side effects and complications were identified. CONCLUSION: In 2009 pandemic influenza A (H1N1), hospital treatment was needed in younger patients. Early intensive care was needed in pneumonia patients accompanying wheezy respiration, and patients accompanying segmental, lobar, interstitial, mixed pneumonia and lung effusion.
