Research progress on extracellular vesicles and bone regeneration
10.12016/j.issn.2096-1456.2019.02.009
- Author:
WEI Shimin
1
,
2
;
WANG Yuanjing
1
,
2
;
HUANG Wen
1
,
2
;
QU Yili
3
,
4
Author Information
1. State Key Laboratory of Oral Diseases &
2. National Clinical Research Center for Oral Diseases, Sichuan University
3. 1.State Key Laboratory of Oral Diseases &
4. National Clinical Research Center for Oral Diseases, Sichuan University 2.Departmenr of Implantology, West China Hospital of Stomatology, Sichuan University
- Publication Type:Review
- Keywords:
Extracellular vesicles;
Exosomes;
Matrix vesicles;
Mesenchymal stem cell;
Bone regeneration;
Angiogenesis;
Mineralization
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2019;27(2):110-114
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles (EVs) are lipid bilayers secreted by a variety of cells that contain nucleic acids, proteins, etc. They can be used as a carrier for cell-to-cell communication. In related research on bone regeneration, mechanisms for transmitting regeneration signals to target cells to achieve the desired goal of osteogenesis have become one of the most important and unsolved topics. Therefore, this review aims to explore the role of mesenchymal stem cells and EVs derived from osteoblasts in bone regeneration in four processes, immunity, angiogenesis, osteogenesis and mineralization, and to provide new ideas for basic and clinical research.
- Full text:胞外囊泡与骨再生研究进展.pdf
