Post-infectious Bronchiolitis Obliterans and Subpleural Cysts in a 30-month-old Boy with Down Syndrome
- Author:
NURDIYANA N
1
Author Information
1. Department of Paediatrics, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia.
- Collective Name:NURDIYANA N; FAIZAH MZ; HASNIAH AL
- Publication Type:Case Reports
- Keywords:
bronchiolitis obliterans;
Down syndrome;
subpleural cyst
- From:Medicine and Health
2019;14(1):252-258
- CountryMalaysia
- Language:English
-
Abstract:
Post-infectious bronchiolitis obliterans is a rare disease that may occur following
a microbiological insult towards the lower respiratory tract causing a severe form
of chronic obstructive airway disease. Subpleural lung cyst may occur in 20-36%
of Down syndrome. We report a case of a 30-month-old Down syndrome child
who had interesting radiological concurrent findings of bronchiolitis obliterans with subpleural cysts on High Resolution Computed Tomography (HRCT) thorax.
This patient was born premature and had early onset pneumonia during the
neonatal period. Subsequently, he had three episodes of pneumonias at 18, 19
and 26 months. He presented with recurrent symptoms of cough, wheeze, rapid
breathing and had features of persistent airway obstruction characterized by
chest hyperinflation, persistent tachypnoea with crepitations and rhonchi despite
on regular bronchodilators. The only positive culture was Influenza B from his
nasopharyneal aspirate culture. To our knowledge, this is the first reported case
with both radiological entities in a child with Down syndrome.
- Full text:12.2019my0124.pdf
