Haplotype analysis of leptin gene polymorphisms in obesity among Malays in Terengganu, Malaysia population
- Author:
Amiratul Athirah Shamsuddin, BSc
1
Author Information
- Collective Name:Aryati Ahmad, PhD 1;Wan Rohani Wan Taib, PhD 2
- Publication Type:Journal Article
- Keywords: A19G; G2548A; H1328080; Haplotype, Leptin; Obesity; Polymorphisms
- From: The Medical Journal of Malaysia 2018;73(5):281-258
- CountryMalaysia
- Language:English
- Abstract: Introduction: The prevalence of overweight and obesity has developed the critical global threat which leads to metabolic risks and mortality. A Leptin hormone that regulates the food intake as well as food expenditure is encoded by Leptin gene. The gene has shown a pivotal role in obesity pathogenesis. This study was sought to determine the SNPs and haplotype association of the Leptin gene that were assigned as G2548A, H1328080, and A19G with obesity among Malays in Terengganu, Malaysia
- Full text:6.2018my1326.pdf
