Research progress on the factors influencing the biological characteristics of dental pulp stem cells
10.12016/j.issn.2096-1456.2019.04.013
- Author:
HU Huiting
1
;
YU Fenglin
2
;
ZHAO Yueping
1
Author Information
1. Stomatology College of Jinan University
2. Life Science and Technology College of Jinan University
- Publication Type:Review
- Keywords:
Dental pulp stem cells;
Biological characteristics;
Influencing factors;
Induction conditions;
Differentiation;
Tissue engineering;
Regenerative medicine
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2019;27(4):268-272
- CountryChina
- Language:Chinese
-
Abstract:
Dental pulp stem cells (DPSCs) are mesenchymal stem cells derived from dental pulp tissue with self-renewal, high proliferative capacity and multidirectional differentiation potential. Under appropriate induction conditions, DPSCs can be differentiated into various types of cells, such as osteoblasts, odontoblasts, chondrocytes, adipocytes, and neuronal cells. DPSCs have been gradually applied to clinical trials and preclinical studies and are important seed cells in the field of periodontal tissue engineering and regenerative medicine. In this paper, the factors affecting the biological characteristics of DPSCs are reviewed together with a review of recent literature published worldwide. The results of the literature review show that the biological characteristics of DPSCs can be influenced by many factors, such as tissue source, culture method, environment and induction conditions, which has guiding significance for research and applications of DPSCs.
- Full text:牙髓干细胞生物学特性影响因素的研究进展.pdf
