Squamous Cell Carcinoma of the Supraglottic Larynx Treated with Radiation Therapy.
- Author:
Charn II PARK
1
;
Kwang Hyun KIM
Author Information
1. Department of Therapeutic Radiology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Squamous cell carcinoma;
Supraglottic larynx;
Radiation therapy;
5-year survival rate
- MeSH:
Carcinoma, Squamous Cell*;
Follow-Up Studies;
Humans;
Larynx*;
Lymph Nodes;
Neck;
Neoplasm Metastasis;
Retrospective Studies;
Survival Rate;
Voice
- From:Journal of the Korean Society for Therapeutic Radiology
1989;7(1):37-44
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sixty-six patients with squamous cell carcinoma of the supraglottic larynx received irradiation with curative intent between 1979 and 1985 were retrospectively analysed. All patients had a minimum follow-up of 4 years. Of the entire group consisting of 73% T3 and T4 lesions and 58% lymph node metastases, a 5-year acturial survival rate was 31.3%. A 5-year acturial survival rates for stage II, III andIV were 60.7%, 46.7% and 13.5% respectively (p<0.05). Patients without lymphnode metastases had better survival rate than those with costive lymphnode metastases(54.8% vs 12.2%) (p<0.005). Surgical salvage rate was 4/7 (57%). Three patients developed distant metastases. Major complications requiring surgery were seen in 11% Radiation therapy alone with surgical salvage was an effective, voice preserving treatment for stage I, II and selected III carcinoma of the supraglottic carcinoma, however planned combined treatment with surgery and radiation therapy is advised for stage III andIV carcinoma of the supraglottic larynx with resectable neck disease.
