CNS germinoma with extensive calcification: An unusual histologic finding
- Author:
Tan Geok Chin
1
,
2
Author Information
1. Department of Pathology and Laboratory Medicine, Nationwide Children&rsquo
2. s Hospital, Columbus OH 43205, USA.
- Collective Name:Geok Chin Tan; Sugunah Sallapan; Kellie Haworth; Jonathan Finlay; Daniel R. Boue’; Christopher R. Pierson
- Publication Type:Case Reports
- Keywords:
Germinoma;
germ cell tumour;
calcification;
CNS;
paediatric
- MeSH:
Germinoma
- From:The Malaysian Journal of Pathology
2019;41(1):71-73
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: Intratumoral calcification is a feature that is more often observed in pineal parenchymal tumour than germinoma. We describe a 13-year-old male with pineal region germinoma demonstrating extensive intratumoral calcification. Case report: He presented with worsening headache that was associated with fatigue, nausea and vomiting. Radiologic examination revealed a multilobular mass in the pineal region with internal calcifications. Biopsy showed a pure germinoma with unusually extensive calcification. Discussion: Although a diagnosis may be suggested with a careful evaluation of imaging, there is no pathognomonic pattern. Thus, histologic verification is necessary for most pineal region masses.
- Full text:5.2019my0996.pdf
