Primary follicular lymphoma of the pancreas: A rare tumour mimicking pancreatic carcinoma
- Author:
Sugunah Sallapan
1
Author Information
1. Departments of Pathology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
- Collective Name:Sugunah Sallapan; Nor Zailin ABu Bakar; Razman Jarmin; Noraidah Masir; Fazarina Mohammed
- Publication Type:Case Reports
- Keywords:
Non-Hodgkin lymphoma;
primary pancreatic lymphoma (PPL);
follicular lymphoma;
pancreas;
obstructive jaundice
- MeSH:
follicular lymphoma
- From:The Malaysian Journal of Pathology
2018;40(3):359-371
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: Primary pancreatic lymphomas are extremely rare. Clinically, primary pancreatic lymphoma mimics symptoms of carcinoma of the pancreatic head. Clinical and radiological features may overlap with other pancreatic conditions such as carcinoma, neuroendocrine tumours and autoimmune pancreatitis. Case Report: We report a case of a 75-year-old man who presented with symptoms of obstructive jaundice. Ultrasonography and computed tomography (CT) showed an illdefined lobulated soft tissue lesion at the head/uncinate process of the pancreas measuring 4.5 x 4.9 x 5.8 cm. The patient underwent pancreaticoduodenectomy for suspected pancreatic head/uncinate process carcinoma. Histopathology and immunohistochemical assessment of the pancreatic lesion established the diagnosis of a low-grade follicular lymphoma. Discussion: Clinical and imaging features of primary pancreatic lymphoma may often overlap with pancreatic carcinoma. There is a value of obtaining preoperative tissue diagnosis such as tissue biopsy and fine needle aspiration (FNA) cytology with or without flow cytometry to make an accurate diagnosis of non-Hodgkin lymphoma and alleviate the need of more radical surgery in pancreatic lymphoma.
- Full text:5.2018my0984.pdf
