Anticariogenic properties of Solanum ferox L. ethanol extract
- Author:
Siti Zaleha Raduan
;
Khairah Nasrin Abdul Khalid
;
Mark Fitchell Ak Jihek
;
Sivagami Ganasan
;
Umi Syazana Salim
;
Muhammad Wahizul Haswan Abdul Aziz
- Publication Type:Journal Article
- Keywords:
Antibiofilm;
Anticariogenic;
Solanum ferox L.,;
Streptococcus pyogenes;
Staphylococcus aureus
- From:
Annals of Dentistry
2019;26(1):22-29
- CountryMalaysia
- Language:English
-
Abstract:
Solanum ferox L. is a plant species which belongs to the Solanaceae family and the genus Solanum. The
Solanum genus was found to exhibit anticariogenic activity and was traditionally used to treat oral diseases.
However, there is no scientific study done specifically for Solanum ferox L. Hence the aim of the study is to
determine the anticariogenic properties of flesh and leaf of ethanolic extract of Solanum ferox L. Alkaloids,
flavonoids and tannins were detected in the leaf ethanolic extract via preliminary phytochemical screening.
The presence of these phytochemicals may contribute to the anticariogenic activity. Treatment with different
concentrations of flesh and leaf of ethanolic extract were used against Streptococcus pyogenes and
Staphylococcus aureus via the method of agar well diffusion to indicate zones of inhibition. The antibiofilm
activity of the flesh and leaf ethanolic extracts was tested. The flesh and leaf ethanolic extracts possess
antimicrobial activity dose-dependently and positive antibiofilm activity against respective pathogens. The
flesh ethanolic extract has stronger anticariogenic activity compared to leaf ethanolic extract against
respective pathogens. Streptococcus pyogenes exhibited higher susceptibility as compared to Staphylococcus
aureus. In conclusion, it has been shown that the ethanolic extract of Solanum ferox L. exhibit anticariogenic
properties against Streptococus pyogenes and Staphylococcus aureus.
- Full text:9.2019my0120.pdf
