Hypersensitivity to ticagrelor and low response to clopidogrel: a case report
10.5415/apallergy.2017.7.1.51
- Author:
Jing DAI
1
;
Shuzheng LYU
;
Changjiang GE
Author Information
1. Department of Cardiology, Capital Medical University Affiliated to Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China. shuzheng@medmail.com.cn
- Publication Type:Case Report
- Keywords:
Antiplatelet therapy;
Hypersensitivity;
Low response;
Ticagrelor;
Clopidogrel;
Warfarin
- MeSH:
Acute Coronary Syndrome;
Aspirin;
Humans;
Hypersensitivity;
Risk Factors;
Stents;
Thrombosis;
Warfarin
- From:
Asia Pacific Allergy
2017;7(1):51-53
- CountryRepublic of Korea
- Language:English
-
Abstract:
Ticagrelor is widely used to treat acute coronary syndrome. Hypersensitivity reaction of ticagrelor is rarely recognized. A low response to clopidogrel, which occurs in up to 23% of patients, is an independent risk factor for stent thrombosis. Management of patients with a low response to clopidogrel and ticagrelor hypersensitivity who are undergoing antithrombotic therapy remains to be a challenge. Herein, we report a patient with low response to clopidogrel and ticagrelor hypersensitivity, who was successfully managed using aspirin and warfarin.