Gastrointestinal Stromal Tumor of the Rectum in a Pediatric.
- Author:
Min Young YUN
1
;
Sun Keun CHOI
;
Yun Suk HUR
;
Kun Young LEE
;
Sei Joong KIM
;
Young Up CHO
;
Seung Ick AHN
;
Kee Chun HONG
;
Suk Hwan SHIN
;
Kyung Rae KIM
;
Ze Hong WOO
Author Information
1. Department of Surgery, Inha University College of Medicine, Incheon, Korea. woopark@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Gastrointestinal stromal tumor (GIST);
Rectum;
Pediatric patient
- MeSH:
Child;
Colon;
Desmin;
Diagnosis;
Esophagus;
Gastrointestinal Stromal Tumors*;
Gastrointestinal Tract;
Humans;
Male;
Proto-Oncogene Proteins c-kit;
Rectum*;
Stomach;
Vimentin
- From:Journal of the Korean Surgical Society
2006;71(2):161-165
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gastrointestinal stromal tumors are the most common subset of mesenchymal tumors that arise from the gastrointestinal tract. They most commonly arise in the stomach, followed by the small bowel and, rarely, the rectum, esophagus and colon. Gastrointestinal stromal tumors and the specific c-kit protein (CD117)-positive mesenchymal tumors, have been sporadically reported in the rectum. We report here on a 12-year-old boy who underwent low anterior resection of huge gastrointestinal stromal tumor of the rectum. The diagnosis was confirmed by immunohistochemical staining of the tumor. The specimen was revealed to be a polypoid fungating tumor that, measured 6.0 x 6.0 cm in size, which consisted histologically of spindle-shaped cells. The tumor cells were positive for c-kit, vimentin, S-100, desmin, and SMA, although the results of the CD34 test were negative. In general, Gastrointestinal stromal tumors of the rectum predominantly occur between the sixth and seventh decades and they are rarely seen in individuals less than 40 years of age. To the best of our knowledge, our case is the youngest reported patient in the English literature who had as gastrointestinal stromal tumor of the rectum.
