Knowledge, attitudes, and practices survey of drug allergy among healthcare practitioners in central China: a multicenter study
10.5415/apallergy.2016.6.2.105
- Author:
Yin WANG
1
;
Rongfei ZHU
;
Nan HUANG
;
Wenjing LI
;
Lin YANG
;
Shucheng ZHANG
;
Guanghui LIU
Author Information
1. Department of Allergy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China. zrf13092@163.com
- Publication Type:Multicenter Study
- Keywords:
Knowledge;
Attitude;
Practice, Drug allergy, Healthcare practitioner
- MeSH:
Anaphylaxis;
Anonyms and Pseudonyms;
China;
Cross-Sectional Studies;
Delivery of Health Care;
Drug Hypersensitivity;
Education;
Epinephrine;
Glucocorticoids;
Histamine Antagonists;
Humans;
Hypersensitivity;
Immunoglobulin E;
Mortality;
Penicillins;
Skin Tests;
Students, Medical;
Surveys and Questionnaires
- From:
Asia Pacific Allergy
2016;6(2):105-111
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Drug allergy (DA) is one of the most important contributors to iatrogenic morbidity and mortality. Currently DA remains a major challenge for healthcare practitioners (HCPs). OBJECTIVE: To assess the knowledge, attitudes and practices of DA among HCPs in Central China. METHODS: A 25-item self-administered DA questionnaire were developed and applied in our study. The questionnaire covered 3 domains: knowledge, attitudes, and practice patterns. From July 2015 to October 2015, HCPs in 7 cities of Central China anonymously participated in the cross-sectional study. RESULTS: A total of 350 HCPs participated the study, 91 questionnaires uncompleted and 259 were analyzed. Among the respondents, 166 (64.1%) were doctors, 55 (21.2%) were nurses and 38 (14.7%) were medical students. The mean knowledge precision was 59.8%. HCPs agreed that drug induced immediate allergic reactions were IgE mediated (83.4%) and happened within 6 hours after drug administration (89.6%), and epinephrine was the first choice for drug induced anaphylaxis (79.5%). They also agreed that penicillin skin test was valuable to predict allergic reaction (88.4%). However, high proportion of HCPs (66.0%) believed glucocorticoids had an impact on drug skin test rather than antihistamines (4.2%), 47.1% never performed positive and negative control during skin test. More than 90% of the respondents would take patients' allergic history before drug administration, 98.8% agreed that they should receive advanced training of DA knowledge and practice. CONCLUSION: The HCPs demonstrated a low level of knowledge regarding DA. Advanced education is urgently needed for better understanding and filling the gaps exist in knowledge and clinical practice of DA.
