Association of insulin resistance with bronchial hyperreactivity
10.5415/apallergy.2014.4.2.99
- Author:
Kyung Mook KIM
1
;
Sun Sin KIM
;
So Hee LEE
;
Woo Jung SONG
;
Yoon Seok CHANG
;
Kyung Up MIN
;
Sang Heon CHO
Author Information
1. Department of Internal Medicine, Gyeonggi Provincial Medical Center Suwon Hospital, Suwon 440-842, Korea.
- Publication Type:Original Article
- Keywords:
Asthma;
Obesity;
Bronchial hyperreactivity;
Insulin resistance
- MeSH:
Adult;
Asthma;
Body Mass Index;
Bronchial Hyperreactivity;
Bronchial Provocation Tests;
Epidemiologic Studies;
Fasting;
Female;
Forced Expiratory Volume;
Glucose;
Hematologic Tests;
Homeostasis;
Humans;
Insulin Resistance;
Insulin;
Logistic Models;
Lung;
Male;
Methacholine Chloride;
Obesity;
Odds Ratio;
Respiratory Function Tests;
Risk Factors;
Seoul;
Waist Circumference
- From:
Asia Pacific Allergy
2014;4(2):99-105
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Several epidemiologic studies showed the significant association of insulin resistance with asthma. OBJECTIVE: The aim of this study was to evaluate the association of insulin resistance with airway hyperresponsiveness (AHR) in adult population. METHODS: 1,058 subjects who visited to the Seoul National University Hospital Gangnam Center from October 2007 to January 2009 for a routine health check-up were enrolled. All subjects completed a questionnaire, anthropometric measurements such as body mass index (BMI) and waist circumference, blood tests, pulmonary function test, and methacholine bronchial provocation test (MBPT). Insulin resistance was estimated from the homeostasis model of assessment of insulin resistance (HOMA-IR).
