Biphasic anaphylaxis to gemifloxacin
10.5415/apallergy.2012.2.4.280
- Author:
Insu YILMAZ
1
;
Serkan DOĞAN
;
Nuri TUTAR
;
Asiye KANBAY
;
Hakan BÜYÜKOĞLAN
;
Ramazan DEMIR
Author Information
1. Department of Chest Diseases, Faculty of Medicine, Erciyes University, Kayseri 38030, Turkey. insu2004@yahoo.com
- Publication Type:Case Report
- Keywords:
Alpha blocker;
Beta blocker;
Biphasic anaphylaxis;
Gemifloxacin;
ACE inhibitor
- MeSH:
Adrenergic Antagonists;
Aged;
Anaphylaxis;
Ciprofloxacin;
Humans;
Levofloxacin;
Male;
Mesylates;
Middle Aged;
Norfloxacin;
Ofloxacin
- From:
Asia Pacific Allergy
2012;2(4):280-282
- CountryRepublic of Korea
- Language:English
-
Abstract:
Anaphylaxis have been documented as adverse effects of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin, and moxifloxacin. However resistant and biphasic anaphlylactic reactions to gemifloxacin have not been reported to date. Management of severe anaphylaxis in the elderly can be complicated by concurrent medications such as beta (β) adrenergic, alpha (α) adrenergic blockers and angiotensin-converting enzyme (ACE) inhibitors. We report here in the case of a 60-year-old male who was taking on ACE inhibitor, α and β blockers and experienced a severe, resistant and biphasic anaphlylactic reaction to gemifloxacin mesylate.