Relationship between sensitivity to dyspnea and fluctuating peak expiratory flow rate in the absence of asthma symptoms
10.5415/apallergy.2012.2.1.49
- Author:
Kuniyoshi KAMIYA
1
;
Kumiya SUGIYAMA
;
Masao TODA
;
Sayo SODA
;
Naoya IKEDA
;
Fumiya FUKUSHIMA
;
Hirokuni HIRATA
;
Yasutsugu FUKUSHIMA
;
Takeshi FUKUDA
Author Information
1. Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Mibu, Tochigi 321-0293, Japan. sugiyama@dokkyomed.ac.jp
- Publication Type:Original Article
- Keywords:
Asthma;
Asthma exacerbation;
Peak expiratory flow;
Severity
- MeSH:
Asthma;
Dyspnea;
Forced Expiratory Volume;
Humans;
Peak Expiratory Flow Rate;
Quality of Life;
Risk Factors
- From:
Asia Pacific Allergy
2012;2(1):49-58
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Exacerbation of asthma has a negative impact on quality of life and increases the risk of fatal asthma. One of the known risk factors for patients with a history of near-fatal asthma is reduced sensitivity to dyspnea. OBJECTIVE: We aimed to identify patients with such risk before they experienced severe exacerbation of asthma. METHODS: We analyzed asthma symptoms and peak expiratory flow rate (PEFR) values of 53 patients recorded daily in a diary over a mean period of 274 days. Patients matched their symptoms to one of eight categories ranging in severity from 'absent' to 'severe attack'. We then analyzed the relationship between PEFR and asthma symptoms by dividing the PEFR value by the values of clinical parameters, including asthma symptom level.
