Staged surgical results of functional single ventricle anomalies with pulmonary hypertension
10.7507/1007-4848.201710066
- VernacularTitle:功能性单心室合并肺动脉高压的分期手术结果
- Author:
PAN Yanjun
1
,
2
;
HE Xiaomin
1
,
2
;
CHEN Huiwen
1
,
2
;
ZHENG Jinghao
1
,
2
;
ZHANG Haibo
1
,
2
;
ZHU Zhongqun
1
,
2
Author Information
1. Department of Pediatric Thoracic and Cardiovascular Surgery, Shanghai Children&rsquo
2. s Medical Center, Medical School of Shanghai Jiaotong University, Shanghai, 200127, P.R.China
- Publication Type:Journal Article
- Keywords:
Functional single ventricle anomalies;
pulmonary hypertension;
staged operations
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2018;25(3):183-187
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore current results after staged operations in patients with functional single ventricle anomalies and pulmonary hypertension. Methods We retrospectively analyzed the clinical data of 129 patients with functional single ventricle anomalies and pulmonary hypertension undergoing pulmonary artery banding in our hospital between April 2008 and December 2015. There were 81 males and 48 females. There were 71 patients with double outlet of right ventricle, 17 patients with tricuspid atresia, 7 patients with transposition of great arteries, 33 patients with uni-ventricular heart, and one patient with complete atrio-ventricular septal defect. The surgical results, transition to Glenn procedure and subsequent transition to Fontan procedure were analyzed. Results The 129 patients underwent 159 operations of pulmonary artery banding totally. Hospital mortality was 4.7% (6/129). Nine patients were lost to follow-up. Eighty-seven (67.4%) patients underwent the second-stage Glenn procedure, and 43 patients(33.3%) underwent third-stage Fontan procedure. Two patients died after Glenn and 3 patients died after Fontan separately. There were 32 patients who accompanied with coarctation, interruption of aortic arch, heterotaxy, total anomalous pulmonary venous connection or atrio-ventricular valve regurgitation. Fifteen (46.9%) patients succeeded in transition to Glenn, and 6 (18.8%) patients succeeded in transition to Fontan. Fourteen patients developed obstruction of left ventricular outlet tract or bulbo-ventricular foramen. Conclusion Early pulmonary artery banding is an acceptable strategy for patients with single ventricle anomalies and pulmonary hypertension. Outcomes and results of subsequent Glenn and Fontan procedures are generally good. Accompanied complex anomalies are risk factors for lower ratio of transition to Glenn and Fontan procedure.