Non-intubated, intravenous anesthesia with spontaneous ventilation versus routine intravenous anesthesia in video-assisted thoracoscopic surgery: A randomized controlled trial
10.7507/1007-4848.201708023
- VernacularTitle:保留自主呼吸的非气管插管与双腔气管插管应用于胸腔镜手术的随机对照试验
- Author:
DENG Yufeng
1
;
QI Fenqiang
1
;
LU Jianhua
2
;
LIN Ying
2
;
YUAN Tianzhu
1
Author Information
1. Department of Cardiothoracic Surgery, the 4th Affiliated Hospital of Guangxi Medical University, Liuzhou, 545005, Guangxi, P.R.China
2. Department of Anesthesiology, the 4th Affiliated Hospital of Guangxi Medical University, Liuzhou, 545005, Guangxi, P.R.China
- Publication Type:Journal Article
- Keywords:
Spontaneous ventilation;
non-intubated anesthesia;
video-assisted thoracoscopic surgery
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2018;25(5):411-415
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the feasibility and safety of video-assisted thoracoscopic surgery (VATS) under non-intubated, intravenous anesthesia with spontaneous ventilation. Methods A total of 80 patients undergoing VATS (48 wedge resections, 8 sympathectomies, 24 pleural biopsies) between January 2015 and June 2017 were included. Those patients were randomized into two groups. The 40 patients were enrolled as a treatment group (19 males and 21 females at age of 23.3±10.2 years) and received surgery under non-intubated intravenous anesthesia with spontaneous ventilation. And the other 40 patients were enrolled as a control group (21 males and 19 females at age of 22.2±9.9 years) and received surgery under routine intravenous anesthesia with intubated ventilation. Results Comparing with the control group, the patients of the treatment group had lower white blood cell count (5.8×109±2.4×109 vs. 7.3×109±3.6×109, P<0.001), lower gastrointestinal adverse reaction rate (7.5% vs. 27.5%, P=0.002), lower sore throat rate (5.0% vs. 30.0%, P<0.001), lower cough grade (0.9±0.3 vs 2.1±0.5, P<0.050), shorter drainage time (1.8±1.6 d vs. 3.7±1.8 d, P<0.050) and shorter hospital stay (2.3±1.8 d vs. 5.8±2.3 d, P<0.050). Conclusion Video-assisted thoracoscopic surgery under non-intubated, intravenous anesthesia with spontaneous ventilation is safe and feasible, which also has certain advantages in reducing the postoperative complications and promoting patients' quick recovery from surgery.
