Progress of Th17 cells in chronic rhinosinusitis.
- Author:
Yang WANG
;
Zhenzhen TANG
;
Dongfang YAO
- Publication Type:Journal Article
- MeSH:
Chronic Disease;
Humans;
Rhinitis;
immunology;
Sinusitis;
immunology;
Th17 Cells;
immunology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2016;30(2):161-166
- CountryChina
- Language:Chinese
-
Abstract:
Chronic rhinosinusitis is a common disease and frequently encountered disease in otolaryngology, but the therapeutic effect is not ideal. While its pathogenesis is exploring in the continuously. Found in the recent years, Th17 cells are a new subset of T cells and closely related with inflammatory disorders, autoimmune diseases and cancer. Its differentiation, regulation and biological effects are widely noted as a hot area of research. This review explores the discovery of differentiation and regulation of Th17 cells, the relationship between related cytokines and chronic rhinosinusitis, in order to have a beteer knowledge of chronic rhinosinusitis. This review regards Th17 cells as the main clue, nevertheless, lacking consideration of the impacts of other factors on chronic rhinosinusitis.