Rare earth elements contents and distribution characteristics in nasopharyngeal carcinoma tissue.
- Author:
Xiangmin ZHANG
;
Xiaolin LAN
;
Lingzhen ZHANG
;
Fufu XIAO
;
Zhaoming ZHONG
;
Guilin YE
;
Zong LI
;
Shaojin LI
- Publication Type:Journal Article
- MeSH:
Carcinoma;
Humans;
Lung;
Lung Neoplasms;
Metals, Rare Earth;
chemistry;
Nasopharyngeal Carcinoma;
Nasopharyngeal Neoplasms;
chemistry;
Reference Values;
Tandem Mass Spectrometry
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2016;30(5):366-369
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the rare earth elements(REEs) contents and distribution characteristics in nasopharyngeal carcinoma( NPC) tissue in Gannan region.
METHOD:Thirty patients of NPC in Gannan region were included in this study. The REEs contents were measured by tandem mass spectrometer inductively coupled plasma(ICP-MS/MS) in 30 patients, and the REEs contents and distribution were analyzed.
RESULT:The average standard deviation value of REEs in lung cancer and normal lung tissues was the minimum mostly. Light REEs content was higher than the medium REEs, and medium REEs content was higher than the heavy REEs content. REEs contents changes in nasopharyngeal carcinoma were variable obviously, the absolute value of Nd, Ce, Pr, Gd and other light rare earth elements were variable widely. The degree of changes on Yb, Tb, Ho and other heavy rare earth elements were variable widely, and there was presence of Eu, Ce negative anomaly(δEu=0. 385 5, δCe= 0. 523 4).
CONCLUSION:The distribution characteristic of REEs contents in NPC patients is consistent with the parity distribution. With increasing atomic sequence, the content is decline wavy. Their distribution patterns were a lack of heavy REEs and enrichment of light REEs, and there was Eu , Ce negative anomaly.
