The correlation of serum specific IgE detection and skin prick test in allergic rhinitis.
- Author:
Yinghong ZHANG
1
;
Li ZHU
;
Ke ZHANG
;
Ping ZHANG
;
Yu SONG
;
Chen DU
;
Qingchuan DUAN
;
Furong MA
Author Information
1. Department of Otolaryngology, Peking University Third Hospital, Beijing, 100191, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Allergens;
analysis;
Animals;
Artemisia;
Child;
Dermatophagoides farinae;
Female;
Humans;
Immunoglobulin E;
blood;
Male;
Middle Aged;
Rhinitis, Allergic;
Rhinitis, Allergic, Perennial;
blood;
diagnosis;
etiology;
Sensitivity and Specificity;
Skin Tests;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(2):75-80
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the correlation between serum specific immunoglobin E(sIgE) and skin prick test(SPT) and their differences of the positive rate.
METHOD:One hundred and nine patients with allergic rhinitis were detected the serum slgE. The patients had positive symptoms and signs, positive SPT results with at least one allergen.
RESULT:Specific IgE and SPT results of Dp,Df and Artemisia showed a positive correlation (r = 0.520, 0.4413, 0.764, P < 0.01). sIgE positive rates were 55.0%, 54.1% and 17.4% for Dp, Df and Artemisia respectively, whereas SPT positive rates were 68.8%,79.8% and 27.5% respectively. The difference between the positive rates of the sIgE and SPT was significant (chi2 = 27.93,18. 20,60. 60, are P< 0.01).
CONCLUSION:There was a good correlation between specific IgE and SPT. SPT is more sensitive than sIgE, but SPT can not substitute for slgE,vice versa.
