Analysis of total and specific IgE in serum of carvota mitis pollen-induced allergic rhinitis patients.
- Author:
Min YAO
1
;
Guang MENG
Author Information
1. Department of Laboratory Medicine, Haikou People's Hospital, Haikou, 570208, China. yaoruan@sina.com
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Allergens;
immunology;
Case-Control Studies;
Child;
Child, Preschool;
Female;
Humans;
Immunoglobulin E;
blood;
immunology;
Male;
Middle Aged;
Pollen;
immunology;
Rhinitis, Allergic;
Rhinitis, Allergic, Perennial;
blood;
immunology;
Skin Tests;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(2):78-80
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:Exploring the relationship between total and specific IgE in serum and allergen skin test of carvota mitis pollen-induced allergic rhinitis patients.
METHOD:Four hundred and-twenty-nine carvota mitis pollen-induced allergic rhinitis patients and 243 healthy control subjects were recruited. The experimental group carried out skin tests. and pollen-specific IgE were also examined by BSA-ELISA method. Total IgE in serum of all of the subjects were determined by ELISA.
RESULT:The positive rate of the total IgE level of the patients were much higher than those of the controls (66.2% vs. 15.6%, P < 0.01). No statistically significance was found between the positivity of skin test and serum specific IgE of the experimental group (chi2 = 0.758 8, P > 0.05). The difference between serum-specific IgE and total IgE was statistically significant (chi2 = 50.639, P<0.01). There was no statistical significance of specific IgE and the total IgE in serum between long term residents in Haikou and Hainan Tourisms (P > 0.05).
CONCLUSION:Allergen skin test and carvota mitis pollen-specific IgE are two effective methods for the diagnosis of carvota mitis pollen-induced allergic rhinitis. The detection of total IgE in serum of carvota mitis pollen-induced allergic rhinitis provides a reference value for diagnosis. The relationship between concentration of IgE in serum of the carvota mitis pollen-induced allergic rhinitis and allergen contact duration is waiting for further study.
