Carcinoembryonic antigen increased as initial manifestation of medullary thyroid cancer (report of 2 cases and review of the literature).
- Author:
Xiangmin ZHANG
1
;
Xiaolin LAN
;
Rong LI
;
Keqin LUO
;
Keqiang TIAN
;
Guoxing ZENG
;
Shaojin LI
Author Information
1. Department of Head and Neck, Tumor Hospital of Ganzhou, Ganzhou, 341000, China.
- Publication Type:Case Reports
- MeSH:
Adult;
Carcinoembryonic Antigen;
metabolism;
Carcinoma, Neuroendocrine;
Female;
Humans;
Middle Aged;
Retrospective Studies;
Thyroid Neoplasms;
metabolism;
pathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(8):410-412
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To raise clinical awareness of carcinoembryonic antigen(CEA) increased as initial manifestation of medullary thyroid cancer(MTC) and explore the diagnosis and treatment.
METHOD:Clinical data of 2 cases CEA increased as the initial presentation of MTC were retrospectively analyzed and clinical manifestations of the disease, diagnosis, treatment were also discussed by literature reviewing.
RESULT:Two patients received thyroid ipsilateral lobe total resection, MTC was confirmed by intraoperative frozen pathology, re-total resection of the contralateral lobe and bilateral VI lymph node dissection were performed. Lymph nodes had no metastasis confirmed by pathological frozen examination. CEA returned to normal within 2 months after surgery. No tumor recurrence and metastasis were found after follow-up for 3 to 24 months.
CONCLUSION:CEA increased as the initial presentation MTC was rare and clinical identification of CEA increased disease should be taken into account the MTC as possible. Total thyroidectomy and bilateral VI lymph node dissection was the main surgical treatment for it.
