Analysis on clinical characteristics, treatments and prognostic factors of head and neck non-Hodgkin's lymphoma.
10.13201/j.issn.1001-1781.2012.04.001
- Author:
Jun WANG
1
;
Changping CAI
;
Shifang HE
;
Shili WANG
Author Information
1. Department of Otolaryngology, Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai, 200025, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Child;
Female;
Head and Neck Neoplasms;
diagnosis;
therapy;
Humans;
Lymphoma, Non-Hodgkin;
diagnosis;
therapy;
Male;
Middle Aged;
Prognosis;
Retrospective Studies;
Treatment Outcome;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(4):148-151
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the clinical characteristics, treatments and prognoses of the primary non-Hodgkin's lymphoma (NHL) in head and neck.
METHOD:Clinical manifestations and clinicopathology characteristics of 107 NHL patients in head and neck were analyzed retrospectively.
RESULT:The median age of patients with head and neck NHL was 54 years. The most commonly primary site was tonsil (29 cases, 27.10%), and the secondly primary site was nasal cavity (28 cases, 26.17%). The most common histologic subtype was diffuse large B cell lymphoma(46 cases, 42.99%), and the secondly one was NK/T cell lymphoma(24 cases, 22.43%). We found that the combination of rituximab was superior than that of chemotherapy alone. Prognosis depended on both IPI and histological subtype, and IPI was a more dangerous factor than histological subtype.
CONCLUSION:The primary NHL is a common neoplasm in the head and neck region. Characteristic in age, primary site, histologic subtype, treatment and prognostic factors were helpful to understand and treat non-Hodgkin's lymphoma in head and neck.
