Salvage surgery for recurrent laryngocarcinoma.
- Author:
Xia XU
;
Xiangping LI
;
Xiong LIU
;
Wendong TIAN
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Female;
Follow-Up Studies;
Humans;
Laryngeal Neoplasms;
surgery;
Male;
Middle Aged;
Neoplasm Recurrence, Local;
surgery;
Prognosis;
Retrospective Studies;
Salvage Therapy;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2014;28(7):477-480
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the curative effect and prognosis of salvage surgery performed for recurrent laryngocarcinoma.
METHOD:The clinical data of 43 patients with salvage surgery for recurrent laryngocarcinoma hospitalized in Nanfang Hospital between 2003 and 2011 were analyzed retrospectively. Survival analysis was performed by using Kaplan-Meier method and prognosis factors were analyzed by Log-rank test.
RESULT:After salvage surgery, 10 (23.3%) patients developed postoperative complications. Pharyngocutaneous fistula and infection occurred in 8 (18.6%) patients. Kaplan-Meier analysis showed that patients survived for 3-year (n = 32) and 5-year 25) after salvage surgery were 56.3% and 32.0% respectively. Univariate analysis indicated that clinical stage in the first diagnosis was significantly correlated with 3 year overall survival (P < 10.05). Local recurrence of laryngeal cavity group and preservation of laryngeal function group had a good prognosis respectively, but no sig nificant difference between them.
CONCLUSION:Salvage surgery is a good choice for recurrent laryngeal carcinoma. Outcomes of these patients were correlated with clinical stages. Laryngeal function preserving surgery for local recurrent laryngeal carcinoma can achieve a expected curative effect and prognosis.
