Relationship between otoacoustic emissions and blood-lead levels in school children.
- Author:
Jianyun LIN
1
;
Ruiqing LIU
;
Quandong CHEN
Author Information
1. Department of Otorhinolaryngology, Kunming Children's Hospital, Kunming 650011, China.
- Publication Type:Journal Article
- MeSH:
Audiometry;
Auditory Threshold;
Child;
Environmental Exposure;
Female;
Humans;
Lead;
blood;
Male;
Otoacoustic Emissions, Spontaneous
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2008;22(10):446-448
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the relationship between blood levels of lead and the function states of cochlear outer hair cells (OHC).
METHOD:Two hundred and fifty-six children lived in Pb-Zn mine area and Yiliang country, aged from 6 to 7 years were enrolled in this study. Blood lead (B-Pb) levels were measured. Otoacoustic emission (OAE) tests including transient evoked otoacoustic emissions (TEOAE) and distortion products otoacoustic emission (DPOAE) were also measured in these children.
RESULT:The difference in B-Pb levels between the school children who lived in mine area and children lived in country was significant (P < 0.01). There were negative correlations between the B-Pb levels and the signal to noise ratio (SNR) on DPOAE test in children who lived in country and those lived in mine area (P < 0.01). The difference in relative coefficients of B-Pb levels between the children lived in mine and children lived in country were significant (P < 0.01).
CONCLUSION:The B-Pb levels of children who lived in mine area were higher than that of those lived in country. SNR decreased in plumbism cases. Long-term Pb expose may influence the function of cochlear OHC and higher B-Pb levels may lead to worse function of OHC.
