Expression and its significance of eosinophil major basic protein in chronic rhinosinusitis.
- Author:
Jing HOU
1
;
Bing ZHOU
;
Luo ZHANG
;
Yunchuan LI
;
Ming LIU
;
Yongxiang WEI
;
Qian HUANG
;
Yang WANG
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, Tongren Hospital, Capital University of Medical Science, Beijing 100073, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Blood Proteins;
metabolism;
Case-Control Studies;
Chronic Disease;
Eosinophil Major Basic Protein;
Female;
Humans;
Male;
Middle Aged;
Mucus;
metabolism;
Nasal Mucosa;
metabolism;
Proteoglycans;
metabolism;
Sinusitis;
metabolism;
pathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2008;22(10):454-455
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the expression of eosinophil major basic protein (MBP) in chronic rhinosinusitis (CRS) and discuss the role of MBP in the pathogenesis in CRS.
METHOD:Thirty-eight nasal mucus obtained from CRS patients were used to detect the expression of MBP by Elisa assay. Thirty nasal mucus samples from health people were used as control.
RESULT:The expression of MBP of nasal mucus obtained from CRS patients was obviously higher than that of nasal mucus obtained from control. There was significant statistical difference (P < 0.01).
CONCLUSION:MBP was involved in the formation of CRS.
