The correlation between ultrastructure of lymphatic capillary and neck lymph node metastasis laryngeal carcinoma.
- Author:
Ye LI
1
;
Ding XIN
;
Lianji WEN
;
Chunshun JIN
Author Information
1. Department of Otorhinolaryngology, the Second Hospital of Jilin University, Changchun, China.
- Publication Type:Journal Article
- MeSH:
Aged;
Carcinoma, Squamous Cell;
pathology;
Case-Control Studies;
Female;
Humans;
Laryngeal Mucosa;
pathology;
Laryngeal Neoplasms;
pathology;
Lymph Nodes;
pathology;
Lymphatic Metastasis;
Lymphatic Vessels;
pathology;
ultrastructure;
Male;
Microscopy, Electron, Transmission;
Middle Aged;
Neck;
Neoplasm Staging
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2007;21(6):267-272
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the correlation between ultrastructure of lymphatic capillary in pericancerous tissue and neck lymph node metastasis in laryngeal carcinoma.
METHOD:Transmission electronic microscope was applied to observe and compare ultrastructure of lymphatic capillary in 8 normal laryngeal epithelial tissue and 12 pericancerous tissue of laryngeal cancer.
RESULT:Lymphatic capillary of pericancerous tissue was significantly dilated compared with normal laryngeal tissue. A large amount of endothelial cell junction was open and devoid of basement membrane. Some endothelial cells of lymphatic capillary were destroyed or broken completely.
CONCLUSION:Ultrastructure of lymphatic capillary in pericancerous tissue is an important factor of laryngeal cancer metastasis through lymphatic system. This research offers theoretic basis for laryngeal carcinoma metastasis mechanism and prevention.
