The curative effect of corticosteroid on acute otitis media with middle ear effusion.
- Author:
Chunfang WANG
1
;
Zheng LIU
;
Xiaowen HUANG
;
Kai XU
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
- Publication Type:Journal Article
- MeSH:
Child;
Child, Preschool;
Female;
Glucocorticoids;
therapeutic use;
Humans;
Infant;
Male;
Otitis Media;
drug therapy;
Otitis Media with Effusion;
drug therapy;
Prospective Studies
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2007;21(4):167-168
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the curative effect of corticosteroid on acute otitis media (AOM) with middle ear effusion.
METHOD:Forty-three children (43 ears) with AOM and abnormal tympanogram were enrolled in a prospective, randomized trial. Twenty-three cases (23 ears) were treated with Dexamethasone and Cefuroxime Sodium, while the other 20 cases (20 ears) were only treated with Cefuroxime Sodium.
RESULT:The period of normalization of tympanometric findings in Dexamethasone treatment group was (54.6+/-6.2) days, which was much longer than that in the group without Dexamethasone treatment (38.5+/-6.1). Three months after treatment, the curative rate of Dexamethasone treatment group was higher than that of the group without Dexamethasone treatment.
CONCLUSION:Corticosteroid can obviously improve middle ear effusion and shorten the duration of middle ear effusion of AOM in the first 2 weeks. To some extent, corticosteroid can also improve middle ear effusion in long term. It indicates that corticosteroid be used as an effective adjunctive drug in treating AOM with middle ear effusion.
