The value of frozen section examination in thyroid surgery.
- Author:
Lei ZHANG
1
;
Wenya LI
;
Mei JIN
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou, 310016, China. dr_zhanglei@yahoo.com.cn
- Publication Type:Case Reports
- MeSH:
Adolescent;
Adult;
Aged;
Female;
Frozen Sections;
methods;
Humans;
Male;
Middle Aged;
Retrospective Studies;
Sensitivity and Specificity;
Thyroid Gland;
pathology;
Thyroid Nodule;
diagnosis;
pathology;
surgery;
Thyroidectomy;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2007;21(7):299-301
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To research the value of frozen section examination for intraoperation diagnosis of thyroid nodule and determination of extent of thyroidectomy.
METHOD:A retrospective evaluation of a group of 1 057 patients with thyroid nodular disease was analyzed. The group was divided into frozen section examination group (FS group) and non-frozen section examination group (NFS group).
RESULT:There were 750 cases in FS group. The diagnosis made by frozen section examination was carcinoma in 117; benign lesion in 626. Diagnosis was deferred in 7 patients. The final pathology diagnosis was carcinoma in 127; benign lesion in 623. The sensitivity, specificity, accuracy and disaccord rate of frozen section examination were 95. 9%, 100. 0%, and 98. 4%, and 1. 6%, respectively. There were 307 cases in NFS group, and the final pathology diagnosis was carcinoma in 30; benign lesion in 277. The disaccord rate with clinical diagnosis was 9. 77%. The binomial distribution analysis indicate that the difference of disaccord rate between the FS group and the NFS group was remarkable ( P <0. 01).
CONCLUSION:Frozen section examination has value in diagnosing the thyroid nodular, and is capable of determination of the extent of thyroidectomy.
