Surgical excision and botulinum toxin A injection for vocal process granuloma.
- Author:
Lijing MA
;
Yang XIAO
;
Jingying YE
;
Qingwen YANG
;
Jun WANG
- Publication Type:Journal Article
- MeSH:
Anesthesia, General;
Botulinum Toxins;
administration & dosage;
Granuloma;
drug therapy;
surgery;
Humans;
Injections;
Intubation, Intratracheal;
Laryngeal Mucosa;
Laryngeal Muscles;
Laryngeal Neoplasms;
drug therapy;
surgery;
Laryngoscopes;
Larynx;
Microsurgery;
Postoperative Period;
Recurrence;
Vocal Cords;
Wound Healing
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(2):140-143
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the efficacy of treatment with microsurgery in combination with local injection of type A botulinum toxin for vocal process granuloma.
METHOD:28 patients with vocal process granuloma received endotracheal intubation under general anesthesia. The lesion was removed with micro-scissor and CO2 laster under a self-retaining laryngoscope and microscope. The incision and mucous membrane surrounding the wound was closed with 8-0 absorbable suture. 4-point injection of botulinum toxin type A 8-15 u was then performed along the thyroarytenoid muscle and arytenoid muscle of the same side. Postoperative medication was administered based on disease causes.
RESULT:All patients experienced vocal cord dyskinesia of the injected side 2-3 days after surgery. At 1 month after the surgery, wound healing was good in all the 28 patients, and the vocal cord movement was limited at the injected side. At 3 months, movement of the bilateral vocal cords was normal, and the vocal cord process mucosa was smooth. Patients were followed up for more than a year, and only one patient had recurrence in 2 months after surgery. The cure rate was 96. 4%.
CONCLUSION:Combination of laryngeal microsurgery and type A botulinum toxin local injection can shorten the treatment course of vocal process granuloma.
