Allergic inflammation in respiratory system.
- Author:
Lifeng AN
;
Yanshu WANG
;
Lin LI
- Publication Type:Journal Article
- MeSH:
Asthma;
physiopathology;
Cytokines;
immunology;
Humans;
Hypersensitivity;
physiopathology;
Inflammation;
physiopathology;
Respiratory System;
physiopathology;
Rhinitis, Allergic;
physiopathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(3):283-287
- CountryChina
- Language:Chinese
-
Abstract:
The pathophysiology of allergic disease such as asthma and allergic rhinitis tell the similar story: when the endogenous and exogenous inflammatory mechanisms occur disorder, the body may begin with inflammatory cell activation, namely through the release of cytokine and inflammatory mediator role in the corresponding target cells, activate the sensory nerve fiber, acting on the cell organ specificity effect, clinical symptoms. This article is divided into the following five parts focused on the research progress of allergic inflammatory diseases: (1) inflammatory cells; (2) staphylococcus aureus superantigen; (3) small molecules (cytokines, inflammatory mediators, lipid classes medium); (4) nerve fibers and effect cells; (5) genetic and epigenetic factors.