A study of intratumor microvessel density and lymph node micrometastases of pN0 supraglottic laryngeal squamous cell carcinoma.
- Author:
Binghua LI
1
;
Yaping XU
;
Lizhong SU
;
Mingyuan CHEN
Author Information
1. Department of Otolaryngology, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China. jackbhlee@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Carcinoma, Squamous Cell;
blood supply;
pathology;
Female;
Humans;
Laryngeal Neoplasms;
blood supply;
pathology;
Lymph Nodes;
pathology;
Lymphatic Metastasis;
Male;
Microvessels;
Middle Aged;
Neoplasm Staging
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2009;23(18):824-826
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the correlation between intratumor microvessel density(IMVD) and lymph node micrometastases.
METHOD:IMVD and lymph node micrometastases were stained with CD105 and CK19 antibody by immunohistochemical method of SABC respectively.
RESULT:IMVD marked with CD105 antibody correlated with T stage and lymph node micrometastases (P < 0.01).
CONCLUSION:The result show that IMVD marked with CD105 antibody highly correlated with lymph node micrometastases. It could be a index to evaluate the prognosis of patients with pN0 supraglottic laryngeal squamous cell carcinoma.
