Follicular Dendritic Cell Sarcoma: A Case Report and Review of the Literature.
- Author:
Bo Sik CHOI
1
;
Jin Ho BAEK
;
Young Min SHIN
;
Jong Hyung KIM
;
Hyung Wook KIM
;
Soon Jung LEE
;
Hee Jeong CHA
Author Information
1. Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. jhbaek@uuh.ulsan.kr
- Publication Type:Original Article
- Keywords:
Dendritic cell sarcoma;
Follicular;
Dendritic cells;
Lymph nodes
- MeSH:
Aged;
Antigen Presentation;
Cough;
Dendritic Cell Sarcoma, Follicular;
Dendritic Cells;
Dendritic Cells, Follicular;
Female;
Gastrointestinal Tract;
Germinal Center;
Humans;
Immune System;
Liver;
Lymph Nodes;
Mouth;
Palatine Tonsil;
Pruritus;
Sensation
- From:Cancer Research and Treatment
2010;42(2):121-124
- CountryRepublic of Korea
- Language:English
-
Abstract:
Follicular dendritic cells (FDC) are non-lymphoid, non-phagocytic accessory cells of the immune system and these cells are essential for antigen presentation and regulation of the reactions in germinal centers. Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that shows a low-to-intermediate malignant potential. The most commonly involved sites are the lymph nodes, but FDCS may also occur at a variety of extranodal sites, including the oral cavity, tonsils, gastrointestinal tract and liver. We describe here a 79-year-old woman who had FDCS with extensive lymph node involvement, dry cough, and an itching sensation. The patient improved after systemic chemotherapy.