Advances on the anti-tumor and anti-radiation effect of tea polyphenols in nasopharyngeal carcinoma.
- Author:
Dongjie YUAN
;
Yuanyuan WEI
;
Zhiwen XU
- Publication Type:Journal Article
- MeSH:
Animals;
Antineoplastic Agents, Phytogenic;
pharmacology;
Carcinoma;
Humans;
Nasopharyngeal Carcinoma;
Nasopharyngeal Neoplasms;
drug therapy;
radiotherapy;
Polyphenols;
pharmacology;
therapeutic use;
Radiation-Protective Agents;
pharmacology;
Tea;
chemistry
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2014;28(4):281-284
- CountryChina
- Language:Chinese
-
Abstract:
NPC is a high incidence of malignant tumors of the head and neck, and is currently used mainly radiotherapy based, supplemented by a comprehensive treatment of chemotherapy, radiotherapy and chemotherapy, which have serious complications and serious impact on the treatment of patients and quality of life. Polyphenols are the main component of tea. Studies have shown that tea polyphenols have a significant anti-tumor effect of im proving the effect of radiotherapy and chemotherapy, reducing radiation damage, reducing conventional chemo therapy drugs IC50 and reducing the complications of chemotherapy. Tea polyphenols in the treatment of nasopharyngeal carcinoma has also made great progress. It has a strong inhibition of nasopharyngeal carcinoma cells, and can greatly reduce the occurrence of xerostomia after radiotherapy, which is of important clinical research value.
