Analysis of bacteriology of drug sensitivity in the inactive stage of chronic suppurative otitis media.
- Author:
Shanshan XIONG
;
Min FU
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Anti-Bacterial Agents;
pharmacology;
Chronic Disease;
Drug Resistance, Bacterial;
Female;
Gram-Negative Bacteria;
drug effects;
Gram-Positive Bacteria;
drug effects;
Humans;
Male;
Microbial Sensitivity Tests;
Middle Aged;
Otitis Media, Suppurative;
microbiology;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2014;28(13):932-934
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:Detecting the sensitivities of bacterium in the inactive stage of chronic suppurative otitis media, to guide a clinical rational drug use after the type I tympanoplasty.
METHOD:Collecting 148 hospitalized patients from Guangdong General Hospital diagnosed as inactive stage of chronic suppurative otitis media, who had been dry ear for more than 1 months. Analyse the results of drug sensitivity on the mucosa surfaces of the middle ear.
RESULT:There are 16 species of bacterium, including Staphylococcus aureus, Pseudomonas aeruginosa, Enterobacter cloacae etc. Total positive rate of bacteria was 33.1%, the detectable rate of gram-positive bacteria was 69.4%, gram-negative bacteria was 30.6%. Drug sensitive test demonstrated that vancomycin, linezolid, teicoplanin, rifampicin etc were effective in gram positive bacteria, piperacillin/tazobactam, cefoperazone/sulbactam etc were effective in gram-negative bacteria.
CONCLUSION:Patients with dry ears,who were going to take type I tympanoplasty, still had potential pathogens. Bacterial cultivation and drug sensitive test before operation can guide the clinical medication and prevent infection.
