The expressions of alpha-enolase in the nasopharyngeal cancer tissue.
- Author:
Chao CHENG
1
;
Xiaobin LONG
;
Xin LI
;
Minqiang XIE
;
Menghe GUO
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, Zhujiang Hospital, South Medical University, Guangzhou, 510282, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Biomarkers, Tumor;
metabolism;
Carcinoma;
Case-Control Studies;
DNA-Binding Proteins;
metabolism;
Female;
Humans;
Male;
Middle Aged;
Nasopharyngeal Carcinoma;
Nasopharyngeal Neoplasms;
metabolism;
pathology;
Neoplasm Invasiveness;
pathology;
Neoplasm Staging;
Phosphopyruvate Hydratase;
metabolism;
Tumor Suppressor Proteins;
metabolism;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2011;25(12):554-556
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the meaning of expressions of ENO1 in the nasopharyngeal cancer tissue.
METHOD:By using SP immunohistochemical methods.
RESULT:The positive expressions for ENO1 were 60.0% in the nasopharyngeal cancer tissues,significantly higher than that (27.5%, 11/40) of in inflammatory nasopharyngeal mucosa (P<0.05). The positive expression rate of ENO1 protein in stage T1 + T2 + T3 was higher than that of in patients with T4 (chi2 = 11.424, P<0.05). But there was no significant relationship between expression of ENO1 and lymph node metastasis and postradiotherapy distant metastasis (P>0.05).
CONCLUSION:The results show that ENO1 over expression may play a important role in cell proliferation and canceration of nasopharyngeal cancer.
