Diagnosis and surgical treatment of parathyroid carcinoma.
- Author:
Jiarui CHEN
1
;
Jun LIU
;
Jiadong WANG
Author Information
1. Department of Otolaryngology Head and Neck Surgery, Renji Hospital of Shanghai Jiaotong University, China.
- Publication Type:Journal Article
- MeSH:
Female;
Humans;
Male;
Middle Aged;
Parathyroid Neoplasms;
diagnosis;
surgery;
Prognosis;
Retrospective Studies;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2010;24(12):541-544
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the diagnosis and surgical treatment of parathyroid carcinoma (PTC).
METHOD:Clinical data of 4 PTC cases were analyzed retrospectively. Four patients all had palpable neck mass. Calcium level was (3.25 +/- 0.53) mmol/L, and PTH level was (1210.25 +/- 528.72) ng/L. Frozen section established diagnosis in only one case. Routine histopathology combined with immunohistochemistry established the diagnosis in 3 patients. Parathyroidectomy and ipsilateral subtotal thyroidectomy was performed in 3 patients; endoscopic parathyroidectomy was performed in one patient.
RESULT:They were followed up for 8-60 months, Calcium level and PTH level were normal. No tumor recurrence and metastasis.
CONCLUSION:The diagnosis of PTC is difficult before operation. Routine blood examinations: blood calcium, blood PTH; Imaging examinations: ultrasonography, CT are helpful to diagnosis. Frozen biopsy is not satisfactory. An initial en bloc resection of tumor and adjacent structures contributes most to the prognosis.
