Analysis on the relationship between tensor veli palatini and secretory otitis media in patients with nasopharyngeal carcinoma after radiotherapy.
- Author:
Yiling GAO
1
;
Anzhou TANG
;
Jin LIU
;
Xiaoming WANG
;
Guangyao HE
;
Zhigang MIN
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital, Guangxi Medical University, Nanning, 530021, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Female;
Humans;
Male;
Middle Aged;
Nasopharyngeal Neoplasms;
radiotherapy;
Otitis Media with Effusion;
etiology;
Palatal Muscles;
pathology;
Palate, Soft;
pathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2010;24(16):743-745
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:The analyze the relationship between secretory otitis media (SOM) and injury of tensor veli palatini (TVP) muscle injury after radiotherapy, then to explore the pathogenesis of SOM in patients with nasopharyngeal carcinoma (NPC) after radiotherapy.
METHOD:The cross section area (CSA) of TVP and medial pterygoid (MP) muscle were measured in MRI of 32 patients with NPC before and after radiotherapy, meanwhile the incidence of SOM were surveyed after radiotherapy, then to analyze the relationship between the change of TVP and the incidence of SOM after radiotherapy.
RESULT:Of 48 ears without SOM before radiotherapy, 27 ears developed post-irradiation SOM, including 24 ears with TVP atrophy and 3 ears without TVP atrophy, and 21 ears had no post-irradiation SOM, including 8 ears with TVP atrophy and 13 ears without TVP atrophy. chi2 test showed significant difference (P < 0.01). It indicated that post-irradiation SOM have correlation with TVP atrophy. The more possibility of TVP atrophy occurred after long time radiotherapy.
CONCLUSION:The atrophy of TVP in patients with NPC usually occurs 6 months after radiotherapy, and this may result in the post-irradiation SOM. The pathogenesis of post-irradiation SOM need further study functionally.
