The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV.
- Author:
Xiaowei ZHOU
;
Youjun YU
;
Yuanxin ZHAO
;
Yuejian WANG
;
Zhen LIU
;
Qiuling LIU
- Publication Type:Journal Article
- MeSH:
Benign Paroxysmal Positional Vertigo;
complications;
Dexamethasone;
administration & dosage;
therapeutic use;
Hearing Loss, Sensorineural;
complications;
drug therapy;
Hearing Loss, Sudden;
complications;
drug therapy;
Hearing Tests;
Humans;
Injection, Intratympanic;
Salvage Therapy;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(10):934-936
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV.
METHOD:A total of 63 patients diagnosed with sudden sensorineural hearing loss with BPPV were treated through OPD. Patients were divided into three groups: 20 cases in intratympanic dexamethasone injection as initial treatment (group A); 18 cases in systemic hormone therapy group (group B); 25 cases in intratympanic dexamethasone injection as salvage treatment (group C). In addition, routine drugs were used to all patients.
RESULT:The overall effective rate of group A, B and C in hearing recovery was 60.0%, 38.9% and 48.0%, respectively: (1) No significant difference of hearing recovery was observed among three groups (P > 0.05); (2) A significant difference of hearing recovery was evidenced between group A and C (P < 0.05); (3) A significant difference of hearing recovery was evidenced between group A and C (P < 0.05); (4) No statistically significant difference was found in the hearing recovery between group B and C (P > 0.05).
CONCLUSION:Our data showed that intratympanic dexamethasone should be used as initial therapy for treating the moderate and severe sudden deafness with BPPV.
